Bioactivity of gentamicin-loaded hydroxyapatite/poly(vinyl alcohol)/chitosan composite coatings aimed for orthopedic application Abstract
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Abstract
Following orthopedic surgery, bacterial infection may lead to significant complications related to inflammation in the peri-implant region, including the potential for implant loosening. To address this concern, the surface of metallic implants was modified through the application of bioactive and antibacterial coatings, aiming to mitigate these issues.
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Funding data
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Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja
Grant numbers 451-03- 47/2023–01/200287;451-03-47/2023–01/200023 -
Horizon 2020
Grant numbers 952033
References
Stevanović M, Đošić M, Janković A, Kojić V, Vukašinović-Sekulić M, Stojanović J, Odović J, Crevar-Sakač M, Rhee KY, Mišković-Stanković V. Gentamicin-Loaded Bioactive Hydroxyapatite/Chitosan Composite Coating Electrodeposited on Titanium. ACS Biomater Sci Eng. 2018; 4: 3994–4007. https://doi.org/10.1021/acsbiomaterials.8b00859.
Djošić M, Janković A, Stevanović M, Stojanović J, Vukašinović-Sekulić M, Kojić V, Mišković-Stanković V. Hydroxyapatite/poly(vinyl alcohol)/chitosan coating with gentamicin for orthopedic implants. Mater Chem Phys. 2023; 303: 127766. https://doi.org/10.1016/j.matchemphys.2023.127766.