Characterisation of strontium-substituted hydroxyapatite as potential biomedical material Abstract

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Marija Đošić
Jelena Nikolić
Jovica Stojanović
Nikola Vuković
Marija Marković
Veljko Savić
Vladimir Topalović


Owing to its similarity to the inorganic part of the natural bone, excellent bioactivity, biocompa­ti­bility, and ability to stimulate the osteoconductive process, synthetic hydroxyapatite (HAP) is very often the material of choice for biomedical applications. Diverse ions can be found as substitutes within natural bone structures, each playing a distinct and crucial role in the physiological processes governing the lifecycle of bones. Among them, strontium ion has a very important role for the acceleration of osteogenesis and the inhibition of osteoclasts activity. Current research aims to provide physico-chemical characterization of synthesized HAP and strontium substituted HAP (Sr-HAP) powders obtained by varying strontium concentration (10, 20 and 40 mol.%) in the starting solutions.


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Đošić, M. ., Nikolić, J. ., Stojanović, J. ., Vuković, N. ., Marković, M. ., Savić, V. ., & Topalović, V. . (2024). Characterisation of strontium-substituted hydroxyapatite as potential biomedical material: Abstract. HEMIJSKA INDUSTRIJA (Chemical Industry), 78(1S), 40. Retrieved from
Biomaterials for orthopedic and dental applications

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I. Cacciotti, Cationic and Anionic Substitutions in Hydroxyapatite, in: I.V. Antoniac (Ed.), Handb. Bioceram. Biocomposites, Springer International Publishing, Switzerland, 2016: pp. 146–188.

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