Characterisation of strontium-substituted hydroxyapatite as potential biomedical material Abstract
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Abstract
Owing to its similarity to the inorganic part of the natural bone, excellent bioactivity, biocompatibility, and ability to stimulate the osteoconductive process, synthetic hydroxyapatite (HAP) is very often the material of choice for biomedical applications. Diverse ions can be found as substitutes within natural bone structures, each playing a distinct and crucial role in the physiological processes governing the lifecycle of bones. Among them, strontium ion has a very important role for the acceleration of osteogenesis and the inhibition of osteoclasts activity. Current research aims to provide physico-chemical characterization of synthesized HAP and strontium substituted HAP (Sr-HAP) powders obtained by varying strontium concentration (10, 20 and 40 mol.%) in the starting solutions.
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Funding data
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Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja
Grant numbers 451-03-47/2023–01/200023
References
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A. Ressler, A. Žužić, I. Ivanišević, N. Kamboj, H. Ivanković, Ionic substituted hydroxyapatite for bone regeneration applications: A review, Open Ceram. 6 (2021). https://doi.org/10.1016/j.oceram.2021.100122