Development of an in vitro branched vasculature using bioprinting technique in combination with sacrificial materials Abstract

Glavni sadržaj članka

Natalija Stojanovic
https://orcid.org/0009-0003-3762-7691
Nadja Hansen
Horst Fischer

Apstrakt

Successful vascularization represents a bottleneck in the production of functional, engineered tissue constructs. The current methods of vascularization either rely on cells self-organization into the capillary network, or predesigned, biofabricated vessels that are limited in size and do not allow the replication of complex vascular networks. Proposed strategies for solving this problem include combinations of natural and synthetic hydrogels with different gelation properties, 3D bioprinting and single or multiple cell cultures with endothelial cells. However, producing defined, capillary-sized hollow channels remains to be beyond reach.

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Detalji članka

Kako citirati
Stojanovic, N. ., Hansen, N. ., & Fischer , H. . (2024). Development of an in vitro branched vasculature using bioprinting technique in combination with sacrificial materials: Abstract. HEMIJSKA INDUSTRIJA : : ХЕМИЈСКА ИНДУСТРИЈА, 78(1S), 9. преузето од https://www.ache-pub.org.rs/index.php/HemInd/article/view/1249
Sekcija
Tissue engineering and in vitro tissue and organ culture models

Reference

Andrée B., Ichanti H., Kalies S., Heisterkamp A., Strauß S., Vogt P.M., Haverich A., Hilfiker A. Formation of three-dimensional tubular endothelial cell networks under defined serum-free cell culture conditions in human collagen hydrogels., Sci Rep 2019; 9:p. 5437. doi: 10.1038/s41598-019-41985-6

Pollet A.M.A.O., den Toonder J.M.J. Recapitulating the Vasculature Using Organ-On-Chip Technology., Bioengineering (Basel) 2020, 7:p. 17