Antimicrobial coatings for orthopaedic applications Abstract
Article Sidebar
Main Article Content
Abstract
A significant advance in modern medicine is the introduction of artificial medical devices, including dental and orthopaedic implants and prostheses. This has led to significant improvements in patient well-being and functionality. However, these 'foreign' devices can cause significant complications, of which bacterial infections remain the most common problem. AMR is the broader term for the loss of sensitivity in different microorganisms or viruses towards antibacterial, antiviral, antiparasitic and antifungal substances. It occurs when microorganisms such as bacteria, viruses, fungi, and parasites change in ways that render the treatment schemes used to cure the infections they cause ineffective. The increase in infections by multi-antibiotic-resistant bacteria has become of great concern, especially in hospitals, after orthopaedic surgical procedures.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors who publish with this journal agree to the following terms:Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors grant to the Publisher the following rights to the manuscript, including any supplemental material, and any parts, extracts or elements thereof:
- the right to reproduce and distribute the Manuscript in printed form, including print-on-demand;
- the right to produce prepublications, reprints, and special editions of the Manuscript;
- the right to translate the Manuscript into other languages;
- the right to reproduce the Manuscript using photomechanical or similar means including, but not limited to photocopy, and the right to distribute these reproductions;
- the right to reproduce and distribute the Manuscript electronically or optically on any and all data carriers or storage media – especially in machine readable/digitalized form on data carriers such as hard drive, CD-Rom, DVD, Blu-ray Disc (BD), Mini-Disk, data tape – and the right to reproduce and distribute the Article via these data carriers;
- the right to store the Manuscript in databases, including online databases, and the right of transmission of the Manuscript in all technical systems and modes;
- the right to make the Manuscript available to the public or to closed user groups on individual demand, for use on monitors or other readers (including e-books), and in printable form for the user, either via the internet, other online services, or via internal or external networks.
Funding data
-
HORIZON EUROPE Marie Sklodowska-Curie Actions
Grant numbers 861138
References
World Health Organisation https://www.who.int/news-room/q-a-detail/antimicrobial-resistance
Kenneth E. Thorpe, Peter Joski,, Kenton J. Johnston Health Affairs 2018; 37(4)
Darouiche RO., N Engl J Med 2004; 350(14): 1422e9
Wimley W.C., Hristova K., J Membrane Biol., 2011; 239: 27-34
Stamboulis et al., Antimicrobial surface, GB patent application 146886GB filed 25th February 2014